Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23762131 | 0.77 | HTR3A (0.72) | HTR3ACXCR3MAPTCYP1A2CYP2A6 | |
| SCHEMBL2202877 | 0.74 | HTR3A (0.68) | HTR3ACXCR3MAPTCYP1A2CYP2A6 | |
| SCHEMBL237632 | 0.74 | HTR3A (0.55) | HTR3ACXCR3MAPTPDE10AUSP30 | |
| SCHEMBL1479055 | 0.73 | HTR3A (0.66) | HTR3ACYP1A2 | |
| SCHEMBL605441 | 0.73 | HTR3A (1.00) | HTR3ACYP1A2 | |
| SCHEMBL10832734 | 0.72 | HTR3A (0.69) | HTR3AMAPT | |
| Hydrochloric Acid SCHEMBL1459700 | 0.72 | HTR3A (0.64) | HTR3ACYP1A2 | |
| SCHEMBL10834346 | 0.72 | HTR3A (0.69) | HTR3AMAPT | |
| SCHEMBL9968339 | 0.70 | SMO (0.41) | PDE10A | |
| SCHEMBL1729381 | 0.70 | GRIN2D (0.47) | HTR3ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | disclosed |