Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23573431 | 0.75 | ATM (0.36) | ATM | |
| SCHEMBL4915983 | 0.72 | — | — | |
| SCHEMBL4915987 | 0.72 | — | — | |
| SCHEMBL8323981 | 0.71 | MAPK1 (0.41) | GRIN1GRIN2B | |
| SCHEMBL1583705 | 0.70 | APLNR (0.48) | GRIN1GRIN2BTDP1 | |
| SCHEMBL15970268 | 0.70 | ATM (0.34) | ATM | |
| SCHEMBL23826989 | 0.70 | ATM (0.39) | ATM | |
| SCHEMBL15970415 | 0.70 | ATM (0.34) | ATM | |
| SCHEMBL15970269 | 0.70 | ATM (0.34) | ATM | |
| SCHEMBL23826990 | 0.70 | ATM (0.39) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768966-B1 | COUMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | INFINITY DISCOVERY INC (US) | 2012-03-07 | — | — | EP | disclosed |