Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 6/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.41 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17300225 | 0.91 | ALDH1A1 (0.55) | ALDH1A1ALOX15HSD17B10CYP2C9NR1I2 | |
| SCHEMBL17298626 | 0.84 | ESR1 (0.62) | ALDH1A1ALOX15HSD17B10CYP2C9NR1I2 | |
| SCHEMBL29925195 | 0.80 | ESR1 (0.59) | ALDH1A1ALOX15HSD17B10ESR1ESR2 | |
| SCHEMBL29404885 | 0.80 | ESR1 (0.59) | ALDH1A1ALOX15HSD17B10ESR1ESR2 | |
| SCHEMBL3688722 | 0.80 | ESR1 (0.59) | ALDH1A1ALOX15HSD17B10ESR1ESR2 | |
| SCHEMBL18399455 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10CYP2C9NR1I2 | |
| SCHEMBL15831659 | 0.79 | ESR1 (0.39) | ALOX15HSD17B10ESR1ESR2TSHR | |
| SCHEMBL16253392 | 0.79 | ESR1 (0.53) | ESR1ESR2TDP1TP53AR | |
| SCHEMBL9861813 | 0.79 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10CYP2C9NR1I2 | |
| SCHEMBL13303116 | 0.78 | ESR1 (0.50) | ALDH1A1ALOX15HSD17B10CYP2C9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344627-A1 | LOW MODULUS NEGATIVE TONE, AQUEOUS DEVELOPABLE PHOTORESIST | DESIGNER MOLECULES, INC | 2015-12-03 | — | — | US | disclosed |