Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.41 |
| ▸ | CDC25B | P30305 | 8/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | GJB2 | P29033 | 1/20 | 0.38 |
| ▸ | FGF1 | P05230 | 2/20 | 0.38 |
| ▸ | FGF2 | P09038 | 2/20 | 0.38 |
| ▸ | VEGFA | P15692 | 2/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17300482 | 1.00 | NT5E (0.43) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17305587 | 1.00 | NT5E (0.43) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17300488 | 0.98 | NT5E (0.43) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17305583 | 0.98 | NT5E (0.43) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17299308 | 0.98 | NT5E (0.43) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17300483 | 0.95 | NT5E (0.41) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17305597 | 0.95 | NT5E (0.41) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17305596 | 0.94 | NT5E (0.41) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17299323 | 0.94 | NT5E (0.41) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17299325 | 0.93 | NT5E (0.41) | NT5EPTPN1CDC25BPTPN2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005847-B2 | Anti-HER2 glycoantibodies and uses thereof | ACADEMIA SINICA (TW) | 2018-06-26 | — | — | US | disclosed |
| US-20150344587-A1 | ANTI-HER2 GLYCOANTIBODIES AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344587-A1 | ANTI-HER2 GLYCOANTIBODIES AND USES THEREOF | FCGR1A, FCGR2A, FCER2 | NT5E 138/4885PTPN1 282/4885CDC25B 1636/4885 |
| US-10005847-B2 | Anti-HER2 glycoantibodies and uses thereof | FCGR1A, FCGR2A, FCER2 | NT5E 138/4885PTPN1 282/4885CDC25B 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.