SCHEMBL17299455

SCHEMBL17299455

c1ccc2c(-c3cccc4c3oc3ccccc34)nc(-n3c4ccccc4c4ccc5ccc6c7ccccc7sc6c5c43)nc2c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 5/20 0.33
PIK3CD O00329 2/20 0.33
PIK3CB P42338 2/20 0.33
BRD4 O60885 1/20 0.30
PIK3CA P42336 1/20 0.30
MTOR P42345 1/20 0.30
PIK3CG P48736 1/20 0.30
KCNH2 Q12809 1/20 0.30
BRDT Q58F21 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17299495 0.93 ALOX5 (0.32) PRKDCPIK3CDPIK3CB
SCHEMBL14756493 0.89 ALOX5 (0.32) PRKDCPIK3CDPIK3CBBRDT
SCHEMBL17451726 0.89 PRKDC (0.34) PRKDCPIK3CDPIK3CBBRD4PIK3CA
SCHEMBL17299485 0.88 ALOX5 (0.33) PRKDCPIK3CDPIK3CB
SCHEMBL16919568 0.87 PRKDC (0.36) PRKDCPIK3CDPIK3CBBRD4PIK3CA
SCHEMBL17299402 0.86
SCHEMBL14756518 0.86 PRKDC (0.33) PRKDCPIK3CDPIK3CB
SCHEMBL24803033 0.85 PRKDC (0.34) PRKDCPIK3CDPIK3CBBRD4PIK3CA
SCHEMBL22199894 0.85 PIK3CD (0.33) PRKDCPIK3CDPIK3CB
SCHEMBL24802266 0.84 PRKDC (0.31) PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10003031-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2018-06-19 US disclosed
US-10003031-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2018-06-19 US disclosed
US-20150349276-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2015-12-03 US disclosed
US-20150349276-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150349276-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF ORAI2, ESR1, OR10J3 PRKDC 3316/4885PIK3CD 4410/4885PIK3CB 4614/4885
US-10003031-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof ORAI2, ESR1, OR10J3 PRKDC 3316/4885PIK3CD 4410/4885PIK3CB 4614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.