SCHEMBL17299570

SCHEMBL17299570

c1ccc(-n2c3ccccc3c3ccc4ccc5c6cc(-n7ccc8ccccc87)ccc6oc5c4c32)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
BIRC5 O15392 1/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
BRCA1 P38398 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ATM Q13315 1/20 0.34
MAOB P27338 4/20 0.34
MAOA P21397 1/20 0.34
GLA P06280 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17299517 0.88 KDM4E (0.43) SIRT2SIRT1TSHRHSD17B10MEN1
SCHEMBL17299562 0.85 KDM4E (0.37) SIRT2SIRT1TSHRHSD17B10MEN1
SCHEMBL17299493 0.84 SIRT2 (0.37) SIRT2SIRT1TSHRHSD17B10MEN1
SCHEMBL17299543 0.80 MAOB (0.36) TSHRHSD17B10MEN1ALDH1A1POLB
SCHEMBL25098388 0.79 KDM4E (0.38) SIRT2SIRT1TSHRHSD17B10MEN1
SCHEMBL17990261 0.79 KDM4E (0.41) SIRT2SIRT1TSHRHSD17B10MEN1
SCHEMBL17779595 0.79 BIRC5 (0.45) SIRT2SIRT1BIRC5TSHRHSD17B10
SCHEMBL17990667 0.78 ALDH1A1 (0.36) TSHRHSD17B10MEN1ALDH1A1POLB
SCHEMBL17299587 0.78 KDM4E (0.37) TSHRHSD17B10MEN1ALDH1A1POLB
SCHEMBL17299541 0.78 BIRC5 (0.34) BIRC5KDM4EL3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10003031-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2018-06-19 US disclosed
US-10003031-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2018-06-19 US disclosed
US-20150349276-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2015-12-03 US disclosed
US-20150349276-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150349276-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF ORAI2, ESR1, OR10J3 SIRT2 683/4885SIRT1 926/4885BIRC5 3345/4885
US-10003031-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof ORAI2, ESR1, OR10J3 SIRT2 683/4885SIRT1 926/4885BIRC5 3345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.