Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17300184 | 0.83 | NPC1 (0.43) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL19375764 | 0.83 | SPHK1 (0.49) | CA1CA2F2PLGPLAU | |
| SCHEMBL16005853 | 0.82 | CA1 (0.60) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL24797595 | 0.82 | SPHK1 (0.51) | HSD17B10CA1CA2F2PLG | |
| SCHEMBL2623845 | 0.81 | NPC1 (0.47) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL17823132 | 0.80 | TAAR1 (0.60) | CA1CA2SPHK1GAAMAPT | |
| SCHEMBL17823130 | 0.80 | TAAR1 (0.60) | CA1CA2SPHK1GAAMAPT | |
| SCHEMBL8952281 | 0.80 | KMT2A (0.58) | HSD17B10CA1CA2MEN1RAB9A | |
| SCHEMBL31206931 | 0.79 | SPHK1 (0.45) | HSD17B10CA1CA2F2PLG | |
| SCHEMBL18099876 | 0.77 | HSD17B10 (0.49) | HSD17B10CA1CA2CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170232023-A1 | PEPTIDE-DRUG CONJUGATES | JIARAY PHARMACEUTICALS INC (KY) | 2017-08-17 | — | — | US | disclosed |
| US-9579317-B2 | Peptide-drug conjugates | JIARUI BIOPHARMACEUTICALS, LTD. (CN) | 2017-02-28 | — | — | US | disclosed |
| US-20150343083-A1 | PEPTIDE-DRUG CONJUGATES | JIARAY PHARMACEUTICALS, INC. (KY) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170232023-A1 | PEPTIDE-DRUG CONJUGATES | DNPEP, VIP, PEPD | HSD17B10 2224/4885CA1 34/4885CA2 137/4885 |
| US-20150343083-A1 | PEPTIDE-DRUG CONJUGATES | DNPEP, VIP, PEPD | HSD17B10 2224/4885CA1 34/4885CA2 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.