Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CIT | O14578 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17300179 | 0.82 | HSD17B10 (0.49) | SPHK1CA1CA2F2PLG | |
| SCHEMBL19375764 | 0.80 | SPHK1 (0.49) | SPHK1CA1CA2F2PLG | |
| SCHEMBL16784039 | 0.80 | SPHK1 (0.46) | SPHK1CA1CA2ROCK1MYLK4 | |
| SCHEMBL24475446 | 0.80 | SPHK1 (0.49) | SPHK1F2PLGPLAUPLAT | |
| SCHEMBL27431579 | 0.80 | SPHK1 (0.49) | SPHK1F2PLGPLAUPLAT | |
| SCHEMBL20356318 | 0.79 | TAAR1 (0.43) | SPHK1CA1CA2TAAR1SMN1; SMN2 | |
| SCHEMBL19019941 | 0.79 | MMP3 (0.42) | SPHK1CA1CA2SMN1; SMN2 | |
| SCHEMBL22001798 | 0.79 | TAAR1 (0.43) | SPHK1CA1CA2TAAR1SMN1; SMN2 | |
| SCHEMBL17615149 | 0.79 | TAAR1 (0.43) | SPHK1CA1CA2TAAR1SMN1; SMN2 | |
| SCHEMBL19318327 | 0.79 | TAAR1 (0.43) | SPHK1CA1CA2TAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4108675-A1 | PREPARATION AND USE OF IMMUNOSTIMULATORY COUPLING COMPLEX WHICH IS DELIVERED AND ACTIVATED IN TARGETED MANNER | Yafei Shanghai Biolog Medicine Science & Technology Co., Ltd. (CN) | 2022-12-28 | — | — | EP | disclosed |