SCHEMBL173011

SCHEMBL173011

Nc1cccc(-c2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 1.00
CYP3A4 P08684 3/20 0.58
CASP1 P29466 1/20 0.58
RECQL P46063 1/20 0.58
MAP4K4 O95819 2/20 0.58
MEN1 O00255 3/20 0.57
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.57
LMNA P02545 2/20 0.57
MAPT P10636 2/20 0.57
HPGD P15428 2/20 0.57
KMT2A Q03164 2/20 0.57
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
MECP2 P51608 1/20 0.57
TAAR1 Q96RJ0 1/20 0.57
HSD17B10 Q99714 1/20 0.57
TDP1 Q9NUW8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29625959 1.00 MAOA (1.00) MAOACYP3A4CASP1RECQLMAP4K4
Hydrochloric Acid SCHEMBL7125902 0.97 MAOA (0.95) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL30469285 0.97 MAOA (0.95) MAOACYP3A4CASP1RECQLMAP4K4
Hydrogen Sulfide SCHEMBL28625051 0.97 MAOA (0.95) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL6797870 0.97 MAOA (0.95) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL29726707 0.97 MAOA (0.95) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL17306371 0.97 MAOA (0.95) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL29057846 0.97 MAOA (0.95) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL22104536 0.97 MAOA (0.95) MAOACYP3A4CASP1RECQLMAP4K4
Hydrochloric Acid SCHEMBL30114339 0.97 MAOA (0.95) MAOACYP3A4CASP1RECQLMAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2852 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12575601-B2 Reduction of amines and nitrosamines in cigarette smoke vapors through a filter functionalized with olive tree polyphenols MAGI'S LAB SRL (IT) 2026-03-17 US claimed
CN-116479366-B Chemical activation of self-passivating metals 斯瓦戈洛克公司 2025-05-23 CN claimed
CN-119912864-A Wear-resistant hot-melt traffic marking paint and preparation method thereof 广西兄弟路标涂料有限公司 2025-05-02 CN claimed
CN-119708485-A Biphenyl bridge type thermoplastic polyester imide, preparation method thereof, biphenyl bridge type thermoplastic polyester imide film and application 中国地质大学(北京) 2025-03-28 CN claimed
CN-119552183-A Narrow emission compound based on spirobifluorene and electroluminescent device prepared from narrow emission compound 中国科学院宁波材料技术与工程研究所 2025-03-04 CN claimed
CN-119400835-A Silicon composite material and application thereof 珠海冠宇电池股份有限公司 2025-02-07 CN claimed
CN-117624841-B Basalt insulating composite material and application thereof in operating rod 国网宁夏电力有限公司银川供电公司 2024-10-29 CN claimed
US-20240315323-A1 Reduction of amines and nitrosamines in cigarette smoke vapors through a filter functionalized with olive tree polyphenols MAGI’S LAB SRL (IT) 2024-09-26 US claimed
EP-4434362-A1 CIGARETTE FILTER FUNCTIONALIZED WITH OLIVE TREE POLYPHENOLS Magi's Lab S.r.l. (IT) 2024-09-25 EP claimed
CN-118146699-B High-temperature-resistant fireproof coating and preparation method thereof 潍坊泰兴生物化工有限责任公司 2024-07-16 CN claimed
CN-101747286-A Nano-aperture 30-element triphenylamine rigid macrocyclic compound and preparation method thereof UNIV NANJING INF SCI & TECH 2010-06-23 CN claimed
US-20090292129-A1 PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST ABIOGEN PHARMA S.P.A. (IT) 2009-11-26 US claimed
EP-1986996-A2 A PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST Abiogen Pharma S.p.A. (IT) 2008-11-05 EP claimed
WO-2007088571-A2 A PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST ABIOGEN PHARMA S.P.A. (IT) 2007-08-09 WO claimed
US-6562840-B1 Non-peptidic inhibitors of proteolytic enzymes such as urokinase 3-DIMENSIONAL PHARMACEUTICALS, INC. 2003-05-13 US claimed
EP-1150979-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2001-11-07 EP claimed
US-20010031781-A1 Heteroaryl amidines, methylamidines and guanidines and use thereof as protease inhibitors ILLIG CARL R (US) 2001-10-18 US claimed
US-6291514-B1 Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2001-09-18 US claimed
WO-2000047578-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2000-08-17 WO claimed
US-5260388-A Reacting aromatic diamine with tetracarboxylic anhydride in presence of aromatic dicarboxylic anhydride or monoamine, imidizing; low dielectric characteristics; electronics MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-11-09 US claimed