Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17301252 | 0.90 | KMT2A (0.58) | KMT2AMAPTMEN1CYP3A4TDP1 | |
| SCHEMBL17304613 | 0.89 | KMT2A (0.77) | KMT2AMAPTCYP3A4LMNAHTT | |
| SCHEMBL31321665 | 0.89 | MAPT (0.61) | KMT2AMAPTMEN1CYP3A4TDP1 | |
| SCHEMBL17304614 | 0.88 | KMT2A (0.59) | KMT2AMAPTLMNANPC1ALDH1A1 | |
| SCHEMBL31321697 | 0.88 | KMT2A (0.71) | KMT2AMAPTMEN1CYP3A4TDP1 | |
| SCHEMBL17301256 | 0.88 | KMT2A (0.56) | KMT2AMAPTMEN1CYP3A4TDP1 | |
| SCHEMBL10039541 | 0.86 | KMT2A (0.64) | KMT2AMAPTMEN1NPC1SMN1; SMN2 | |
| SCHEMBL17301260 | 0.86 | KMT2A (0.64) | KMT2AMAPTMEN1LMNANPC1 | |
| SCHEMBL19623998 | 0.86 | KMT2A (0.64) | KMT2AMAPTLMNAHTTNPC1 | |
| SCHEMBL31321618 | 0.85 | MAPT (0.56) | KMT2AMAPTMEN1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344782-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM | FUJIFILM CORPORATION (JP) | 2015-12-03 | — | — | US | disclosed |
| US-9005906-B2 | Tetrahydropyran nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2015-04-14 | — | — | US | disclosed |