SCHEMBL17301252

SCHEMBL17301252

CCCc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(CCC)cc3)c(OC)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.58
MAPT P10636 4/20 0.52
MEN1 O00255 2/20 0.49
CYP3A4 P08684 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PRSS1 P07477 1/20 0.48
ACR P10323 1/20 0.48
NPC1 O15118 3/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
THRB P10828 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
RAB9A P51151 2/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
PLA2G1B P04054 1/20 0.46
ATG4B Q9Y4P1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17301256 0.92 KMT2A (0.56) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL17301262 0.90 KMT2A (0.62) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL17304613 0.85 KMT2A (0.77) KMT2AMAPTCYP3A4NPC1LMNA
SCHEMBL17301222 0.84 MAPT (0.48) KMT2AMAPTL3MBTL1PRSS1ACR
SCHEMBL17304614 0.84 KMT2A (0.59) KMT2AMAPTNPC1LMNATHRB
SCHEMBL4828280 0.84 PRSS1 (0.57) KMT2AMAPTPRSS1ACRNPC1
SCHEMBL30354554 0.83 THRB (0.62) KMT2AMAPTL3MBTL1PRSS1ACR
SCHEMBL10633416 0.83 THRB (0.62) KMT2AMAPTL3MBTL1PRSS1ACR
SCHEMBL17301235 0.83 MAPT (0.55) KMT2AMAPTNPC1THRBSMN1; SMN2
SCHEMBL20110383 0.83 MAPT (0.50) KMT2AMAPTPRSS1ACRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed