Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17302203 | 1.00 | AAK1 (0.41) | AAK1CNR1CTSSCTSKTRPA1 | |
| SCHEMBL17302049 | 1.00 | AAK1 (0.41) | AAK1CNR1CTSSCTSKTRPA1 | |
| SCHEMBL17301886 | 1.00 | AAK1 (0.41) | AAK1CNR1CTSSCTSKTRPA1 | |
| SCHEMBL1709045 | 0.94 | TRPA1 (0.41) | AAK1CNR1CTSSCTSKTRPA1 | |
| SCHEMBL1699000 | 0.94 | TRPA1 (0.41) | AAK1CNR1CTSSCTSKTRPA1 | |
| SCHEMBL1708913 | 0.94 | TRPA1 (0.41) | AAK1CNR1CTSSCTSKTRPA1 | |
| SCHEMBL17302054 | 0.84 | S1PR3 (0.46) | CNR1CTSSCTSKTRPA1NPC1 | |
| SCHEMBL17302048 | 0.82 | S1PR3 (0.43) | CNR1CTSSCTSKTRPA1NPC1 | |
| SCHEMBL17302050 | 0.81 | CNR1 (0.41) | AAK1CNR1CTSSCTSKTRPA1 | |
| SCHEMBL17302197 | 0.81 | CNR1 (0.41) | AAK1CNR1CTSSCTSKTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184383-A1 | ARYL-SUBSTITUTED IMIDAZOLES AND METHODS OF MAKING AND USING SAME | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2015-12-03 | — | — | WO | disclosed |