Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17294505 | 0.91 | GPR84 (0.66) | GPR84FFAR1FFAR4FAAHL3MBTL1 | |
| SCHEMBL17302563 | 0.91 | GPR84 (0.66) | GPR84FFAR1FFAR4FAAHL3MBTL1 | |
| SCHEMBL9576901 | 0.88 | PLA2G1B (0.44) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| Trolamine SCHEMBL27959953 | 0.87 | GPR84 (0.72) | GPR84FFAR1FFAR4ACE2MAPT | |
| Trolamine SCHEMBL7203182 | 0.87 | GPR84 (0.72) | GPR84FFAR1FFAR4ACE2MAPT | |
| Trolamine SCHEMBL28149422 | 0.87 | GPR84 (0.72) | GPR84FFAR1FFAR4ACE2MAPT | |
| SCHEMBL14833428 | 0.85 | PLA2G1B (0.44) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL4432629 | 0.85 | PLA2G1B (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL10955128 | 0.85 | PLA2G1B (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL6552661 | 0.85 | PLA2G1B (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184256-A2 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2015-12-03 | — | — | WO | disclosed |