SCHEMBL17303310

SCHEMBL17303310

CCc1nccc2cc(Br)ccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLAU P00749 2/20 0.47
▸ GRM4 Q14833 1/20 0.43
▸ PDE3A Q14432 4/20 0.42
▸ PDE3B Q13370 3/20 0.42
▸ MAPK1 P28482 4/20 0.37
▸ LMNA P02545 4/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ TDP1 Q9NUW8 2/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ PKM P14618 2/20 0.37
▸ MAPT P10636 1/20 0.37
▸ PLG P00747 1/20 0.37
▸ PLAT P00750 1/20 0.37
▸ CYP1A2 P05177 5/20 0.37
▸ CYP2C9 P11712 4/20 0.37
▸ CYP3A4 P08684 3/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ TSHR P16473 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30881436 1.00 PLAU (0.47) PLAUGRM4PDE3APDE3BMAPK1
SCHEMBL31207249 0.82 PLAU (0.51) PLAUPDE3APDE3BMAPK1LMNA
SCHEMBL24325934 0.82 PLAU (0.51) PLAUPDE3APDE3BMAPK1LMNA
SCHEMBL31206995 0.82 PLAU (0.47) PLAUPDE3APDE3BMAPK1LMNA
SCHEMBL3061217 0.79 GRM4 (0.46) PLAUGRM4PDE3APDE3BMAPK1
SCHEMBL1445946 0.77 SMN1; SMN2 (0.43) PLAUPDE3APDE3BMAPK1LMNA
SCHEMBL2612055 0.76 PDE10A (0.51) PLAUGRM4PDE3APDE3BMAPK1
SCHEMBL18431778 0.76 GRM4 (0.41) PLAUGRM4PDE3APDE3BMAPK1
SCHEMBL3379200 0.76 SMN1; SMN2 (0.49) PLAUGRM4PDE3AMAPK1LMNA
SCHEMBL24325417 0.76 PLAU (0.40) PLAUPDE3APDE3BMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598923-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS The Regents of the University of California (US) 2025-08-13 — — EP disclosed
US-20240197682-A1 METHOD FOR TREATING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 — — US disclosed
US-20240201205-A1 METHOD FOR DETECTING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 — — US disclosed
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 — — US disclosed
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 — — US disclosed
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 — — US disclosed
WO-2024059845-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-21 — — WO disclosed
WO-2024059845-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-21 — — WO disclosed
WO-2015181676-A1 CARBONITRILE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS PFIZER INC. (US) 2015-12-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS MAPT, HTT, PSEN1 PLAU 450/4885GRM4 824/4885PDE3A 1576/4885
US-20240197682-A1 METHOD FOR TREATING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS PRNP, PSEN1, SNCA PLAU 546/4885GRM4 981/4885PDE3A 2468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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