Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24325934 | 0.82 | PLAU (0.51) | PLAUPLGPLATCYP1A2CYP2C19 | |
| SCHEMBL31207249 | 0.82 | PLAU (0.51) | PLAUPLGPLATCYP1A2CYP2C19 | |
| SCHEMBL17303310 | 0.82 | PLAU (0.47) | PLAUPLGPLATCYP1A2CYP2C19 | |
| SCHEMBL30881436 | 0.82 | PLAU (0.47) | PLAUPLGPLATCYP1A2CYP2C19 | |
| SCHEMBL30051661 | 0.79 | TRPA1 (0.38) | CYP1A2CYP2C19ROCK1CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL30050415 | 0.77 | TRPA1 (0.37) | CYP1A2CYP2C19ROCK1CYP2D6CYP2C9 | |
| SCHEMBL30111349 | 0.76 | PLAU (0.51) | PLAUPLGPLATCYP1A2CYP2C19 | |
| SCHEMBL1536295 | 0.76 | PLAU (0.51) | PLAUPLGPLATCYP1A2CYP2C19 | |
| SCHEMBL28216043 | 0.75 | PLAU (0.54) | PLAUPLGPLATCYP1A2CYP2C19 | |
| SCHEMBL30050820 | 0.75 | PDE10A (0.50) | PLAUCYP1A2CYP2C19ROCK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293391-A1 | ISOQUINOLINE AND PYRIDINE BASED CXCR4 ANTAGONISTS | UNIV LEUVEN KATH (BE) | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293391-A1 | ISOQUINOLINE AND PYRIDINE BASED CXCR4 ANTAGONISTS | CXCR4, CCR5, CXCR1 | PLAU 3423/4885PLG 3731/4885PLAT 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.