Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833442 | 0.89 | HSD17B10 (1.00) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL20758125 | 0.82 | HSD17B10 (0.67) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15661558 | 0.81 | HSD17B10 (0.66) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL24871362 | 0.77 | HSD17B10 (0.61) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15660578 | 0.77 | HSD17B10 (0.61) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15661379 | 0.77 | HSD17B10 (0.61) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6264956 | 0.77 | L3MBTL1 (0.65) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL13851465 | 0.76 | TDP1 (1.00) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL12443567 | 0.76 | KMT2A (1.00) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15154928 | 0.76 | HSD17B10 (0.62) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |