Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729947 | 0.93 | BACE1 (0.31) | BACE1 | |
| SCHEMBL1730369 | 0.89 | KDM4E (0.33) | KDM4EPKMBACE1 | |
| SCHEMBL6062480 | 0.88 | BACE1 (0.32) | KDM4EPKMBACE1 | |
| SCHEMBL1728234 | 0.87 | KEAP1 (0.30) | — | |
| SCHEMBL6062485 | 0.87 | DPP4 (0.39) | — | |
| SCHEMBL6062481 | 0.87 | DPP4 (0.39) | — | |
| SCHEMBL1729963 | 0.80 | GFER (0.31) | BACE1 | |
| SCHEMBL1728231 | 0.76 | KEAP1 (0.31) | KDM4EPKMBACE1 | |
| SCHEMBL6062217 | 0.73 | DPP4 (0.38) | — | |
| SCHEMBL1728443 | 0.73 | PPIA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651653-B1 | NOVEL CYANO THIAZOLIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-11-23 | — | — | EP | disclosed |