Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566436 | 0.85 | MEN1 (0.31) | MEN1NPC1ALDH1A1CYP1A2RAB9A | |
| SCHEMBL14566492 | 0.84 | MEN1 (0.33) | MEN1NPC1ALDH1A1CYP1A2RAB9A | |
| SCHEMBL14566406 | 0.84 | MEN1 (0.33) | MEN1NPC1ALDH1A1CYP1A2RAB9A | |
| SCHEMBL14566358 | 0.84 | MEN1 (0.33) | MEN1NPC1ALDH1A1CYP1A2RAB9A | |
| SCHEMBL28120360 | 0.83 | LPAR3 (0.36) | — | |
| SCHEMBL17036899 | 0.83 | CA12 (0.34) | — | |
| SCHEMBL14566426 | 0.82 | MEN1 (0.32) | MEN1NPC1ALDH1A1CYP1A2RAB9A | |
| SCHEMBL12360854 | 0.81 | ALDH1A1 (0.38) | MEN1NPC1ALDH1A1CYP1A2RAB9A | |
| SCHEMBL14566351 | 0.81 | HDAC3 (0.34) | MEN1NPC1ALDH1A1CYP1A2RAB9A | |
| SCHEMBL14566354 | 0.81 | MEN1 (0.31) | MEN1NPC1ALDH1A1CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181624-A2 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF CANCER | IDENIX PHARMACEUTICALS, INC (US) | 2015-12-03 | — | — | WO | disclosed |