Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14665336 | 0.90 | CYP2D6 (0.51) | CYP2D6CYP3A4 | |
| SCHEMBL97643 | 0.89 | CYP3A4 (0.79) | CYP2D6CYP3A4 | |
| SCHEMBL10049618 | 0.87 | CYP2D6 (0.82) | CYP2D6CYP3A4 | |
| SCHEMBL14665399 | 0.86 | CYP2D6 (0.53) | CYP2D6CYP3A4 | |
| SCHEMBL14665398 | 0.86 | CYP2D6 (0.53) | CYP2D6CYP3A4 | |
| SCHEMBL14665373 | 0.86 | CYP2D6 (0.53) | CYP2D6CYP3A4 | |
| SCHEMBL30515122 | 0.85 | CYP3A4 (0.73) | CYP2D6CYP3A4 | |
| SCHEMBL4312545 | 0.85 | CYP3A4 (0.73) | CYP2D6CYP3A4 | |
| SCHEMBL173030 | 0.85 | CYP3A4 (0.73) | CYP2D6CYP3A4 | |
| SCHEMBL1032335 | 0.85 | CYP3A4 (0.73) | CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058975-A1 | Phosphonate Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-03-08 | — | — | US | disclosed |
| US-20100173870-A1 | Phosphonate Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058975-A1 | Phosphonate Compounds | PHPT1, PHOSPHO1, PIK3CA | CYP2D6 3148/4885CYP3A4 2408/4885 |
| US-20100173870-A1 | Phosphonate Compounds | PHPT1, PHOSPHO1, PIK3CA | CYP2D6 3148/4885CYP3A4 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.