Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173053 | 0.89 | CYP2D6 (0.64) | CYP3A4CYP2D6 | |
| SCHEMBL14665315 | 0.89 | CYP3A4 (0.63) | CYP3A4CYP2D6 | |
| SCHEMBL14665317 | 0.89 | CYP3A4 (0.63) | CYP3A4CYP2D6 | |
| SCHEMBL14665360 | 0.89 | CYP3A4 (0.63) | CYP3A4CYP2D6 | |
| SCHEMBL14665311 | 0.89 | CYP3A4 (0.63) | CYP3A4CYP2D6 | |
| Tenofovir Exalidex SCHEMBL8268123 | 0.89 | CYP3A4 (0.98) | CYP3A4CYP2D6 | |
| Tenofovir Exalidex SCHEMBL2299893 | 0.89 | CYP3A4 (0.98) | CYP3A4CYP2D6 | |
| SCHEMBL23015000 | 0.88 | CYP3A4 (0.97) | CYP3A4CYP2D6 | |
| SCHEMBL24722045 | 0.88 | CYP3A4 (0.97) | CYP3A4CYP2D6 | |
| SCHEMBL23014999 | 0.88 | CYP3A4 (0.97) | CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058975-A1 | Phosphonate Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-03-08 | — | — | US | disclosed |
| WO-2011011710-A1 | METHODS OF TREATING VIRAL INFECTIONS | CHIMERIX, INC. (US) | 2011-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058975-A1 | Phosphonate Compounds | PHPT1, PHOSPHO1, PIK3CA | CYP3A4 2408/4885CYP2D6 3148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.