Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | F2R | P25116 | 11/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5494303 | 0.99 | KDM4E (0.41) | KDM4EMAPTRAB9ASMN1; SMN2F2R | |
| Bromide SCHEMBL1730516 | 0.91 | KDM4E (0.41) | KDM4EMAPTRAB9ASMN1; SMN2F2R | |
| Bromide SCHEMBL1729335 | 0.90 | ALDH1A1 (0.43) | KDM4EMAPTRAB9ASMN1; SMN2F2R | |
| Bromide SCHEMBL5486176 | 0.90 | KDM4E (0.44) | KDM4EMAPTRAB9ASMN1; SMN2F2R | |
| Bromide SCHEMBL1731559 | 0.89 | F2R (0.40) | KDM4EMAPTRAB9ASMN1; SMN2F2R | |
| Bromide SCHEMBL1730955 | 0.88 | F2R (0.40) | KDM4EMAPTRAB9ASMN1; SMN2F2R | |
| Bromide SCHEMBL1728955 | 0.85 | KDM4E (0.41) | KDM4EMAPTRAB9ASMN1; SMN2F2R | |
| Bromide SCHEMBL1730571 | 0.85 | F2R (0.46) | KDM4EMAPTRAB9ASMN1; SMN2F2R | |
| Bromide SCHEMBL1729353 | 0.83 | KDM4E (0.46) | KDM4EMAPTRAB9ASMN1; SMN2F2R | |
| SCHEMBL5490666 | 0.83 | KDM4E (0.48) | KDM4EMAPTRAB9ASMN1; SMN2F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |