Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | WHR1 | P49842 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306598 | 0.94 | MEN1 (0.42) | MEN1KMT2AATMTOP1DHODH | |
| SCHEMBL17306596 | 0.91 | MEN1 (0.41) | MEN1KMT2AATMMETAP1TSHR | |
| SCHEMBL17306771 | 0.88 | MEN1 (0.39) | MEN1KMT2AATMMETAP1TSHR | |
| SCHEMBL23921418 | 0.87 | CCR1 (0.40) | MEN1KMT2AMETAP1TSHRHSD17B10 | |
| SCHEMBL17306769 | 0.87 | MEN1 (0.47) | MEN1KMT2AATMMETAP1TSHR | |
| SCHEMBL17306658 | 0.86 | MEN1 (0.46) | MEN1KMT2AATMMETAP1TSHR | |
| SCHEMBL17307040 | 0.86 | MEN1 (0.46) | MEN1KMT2AATMMETAP1TSHR | |
| SCHEMBL17306606 | 0.86 | MEN1 (0.46) | MEN1KMT2AATMMETAP1TSHR | |
| SCHEMBL17306865 | 0.86 | MEN1 (0.39) | MEN1KMT2AATMMETAP1TSHR | |
| SCHEMBL17306568 | 0.85 | MEN1 (0.45) | MEN1KMT2AATMMETAP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |