Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | WHR1 | P49842 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | CCR8 | P51685 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TOP1 | P11387 | 4/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306595 | 0.94 | MEN1 (0.39) | MEN1KMT2AATMWHR1CCR1 | |
| SCHEMBL17306597 | 0.87 | MEN1 (0.33) | MEN1KMT2AATMWHR1CCR1 | |
| SCHEMBL17306615 | 0.86 | MEN1 (0.48) | MEN1KMT2AATMWHR1HPGD | |
| SCHEMBL17306731 | 0.85 | MEN1 (0.49) | MEN1KMT2AATMWHR1HPGD | |
| SCHEMBL22963184 | 0.84 | MEN1 (0.47) | MEN1KMT2AATMWHR1CCR1 | |
| SCHEMBL22963420 | 0.84 | MEN1 (0.50) | MEN1KMT2AATMWHR1CCR1 | |
| SCHEMBL22963277 | 0.84 | MEN1 (0.50) | MEN1KMT2AATMWHR1CCR1 | |
| SCHEMBL22963396 | 0.84 | MEN1 (0.47) | MEN1KMT2AATMWHR1CCR1 | |
| SCHEMBL22963529 | 0.84 | MEN1 (0.47) | MEN1KMT2AATMWHR1CCR1 | |
| SCHEMBL17306596 | 0.83 | MEN1 (0.41) | MEN1KMT2AATMWHR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |