Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | WHR1 | P49842 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306620 | 0.99 | MEN1 (0.50) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306599 | 0.93 | MEN1 (0.55) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17307048 | 0.92 | MEN1 (0.43) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306658 | 0.91 | MEN1 (0.46) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17307040 | 0.91 | MEN1 (0.46) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306606 | 0.91 | MEN1 (0.46) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306578 | 0.90 | HPGD (0.49) | MEN1KMT2AATMWHR1HPGD | |
| SCHEMBL17307021 | 0.90 | HPGD (0.49) | MEN1KMT2AATMWHR1HPGD | |
| SCHEMBL17306442 | 0.90 | MEN1 (0.48) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17307058 | 0.90 | WHR1 (0.47) | MEN1KMT2AATMWHR1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |