Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307064 | 0.95 | PIK3CA (0.50) | WHR1MEN1KMT2AATMPIK3CA | |
| SCHEMBL17307090 | 0.95 | PIK3CA (0.50) | WHR1MEN1KMT2AATMPIK3CA | |
| SCHEMBL17306432 | 0.93 | PIK3CA (0.47) | WHR1MEN1KMT2AATMPIK3CA | |
| SCHEMBL17307093 | 0.92 | KMT2A (0.53) | WHR1MEN1KMT2AATMPIK3CA | |
| SCHEMBL17307061 | 0.91 | CYP1A2 (0.46) | WHR1MEN1KMT2APIK3CAMAP4K4 | |
| SCHEMBL17306710 | 0.90 | CYP1A2 (0.45) | WHR1MEN1KMT2AATMPIK3CA | |
| SCHEMBL17307055 | 0.90 | CYP1A2 (0.45) | WHR1MEN1KMT2AATMPIK3CA | |
| SCHEMBL17307086 | 0.90 | WHR1 (0.42) | WHR1MEN1KMT2AATMPIK3CA | |
| SCHEMBL17306686 | 0.90 | CYP1A2 (0.45) | WHR1MEN1KMT2AATMPIK3CA | |
| SCHEMBL17306656 | 0.90 | MEN1 (0.49) | WHR1MEN1KMT2AATMPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |