Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | WHR1 | P49842 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306594 | 0.99 | MEN1 (0.49) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306751 | 0.92 | ATM (0.43) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306874 | 0.90 | HPGD (0.45) | MEN1KMT2AATMHPGDKDM4E | |
| SCHEMBL17306728 | 0.89 | MEN1 (0.54) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306862 | 0.88 | MEN1 (0.40) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306599 | 0.87 | MEN1 (0.55) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306731 | 0.85 | MEN1 (0.49) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306615 | 0.84 | MEN1 (0.48) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306878 | 0.84 | MEN1 (0.37) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306620 | 0.82 | MEN1 (0.50) | MEN1KMT2AATMWHR1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |