Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 6/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.47 |
| ▸ | WHR1 | P49842 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306594 | 0.91 | MEN1 (0.49) | MEN1KMT2AATMESR1ESR2 | |
| SCHEMBL17306599 | 0.90 | MEN1 (0.55) | MEN1KMT2AATMWHR1NUDT1 | |
| SCHEMBL17306672 | 0.89 | MEN1 (0.50) | MEN1KMT2AATMESR1ESR2 | |
| SCHEMBL22652774 | 0.85 | MEN1 (0.65) | MEN1KMT2AATMWHR1NUDT1 | |
| SCHEMBL17306667 | 0.85 | MEN1 (0.50) | MEN1KMT2AATMWHR1NUDT1 | |
| SCHEMBL17307033 | 0.85 | MEN1 (0.50) | MEN1KMT2AATMWHR1NUDT1 | |
| SCHEMBL18504016 | 0.84 | MEN1 (0.64) | MEN1KMT2AATMWHR1NUDT1 | |
| SCHEMBL17307036 | 0.83 | HPGD (0.53) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306743 | 0.83 | MEN1 (0.49) | MEN1KMT2AATMWHR1NUDT1 | |
| SCHEMBL17306462 | 0.83 | MEN1 (0.49) | MEN1KMT2AATMWHR1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |