Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306804 | 0.90 | KMT2A (0.35) | WHR1KMT2AMEN1ATMMKNK1 | |
| SCHEMBL17306413 | 0.84 | MAPT (0.35) | WHR1KMT2AMEN1ATMKDM4E | |
| SCHEMBL17306878 | 0.83 | MEN1 (0.37) | WHR1KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL17306721 | 0.82 | — | — | |
| SCHEMBL17306979 | 0.81 | CYP1A2 (0.33) | KMT2AMEN1ATMMAPTL3MBTL1 | |
| SCHEMBL17306864 | 0.81 | MEN1 (0.35) | WHR1KMT2AMEN1ATMHPGD | |
| SCHEMBL17307093 | 0.81 | KMT2A (0.53) | WHR1KMT2AMEN1ATMMKNK1 | |
| SCHEMBL17306597 | 0.79 | MEN1 (0.33) | WHR1KMT2AMEN1ATMHPGD | |
| SCHEMBL17307058 | 0.78 | WHR1 (0.47) | WHR1KMT2AMEN1ATMMKNK1 | |
| SCHEMBL17307089 | 0.78 | MKNK1 (0.52) | WHR1KMT2AMEN1ATMMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |