Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | METAP1 | P53582 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | WHR1 | P49842 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306478 | 0.92 | WHR1 (0.45) | KMT2AMEN1METAP1ATMDHODH | |
| SCHEMBL17307074 | 0.92 | WHR1 (0.45) | KMT2AMEN1METAP1ATMDHODH | |
| SCHEMBL17306487 | 0.90 | DHODH (0.40) | KMT2AMEN1METAP1ATMDHODH | |
| SCHEMBL17307080 | 0.89 | DHODH (0.43) | KMT2AMEN1METAP1ATMDHODH | |
| SCHEMBL17306754 | 0.89 | DHODH (0.43) | KMT2AMEN1METAP1ATMDHODH | |
| SCHEMBL17306699 | 0.89 | DHODH (0.43) | KMT2AMEN1METAP1ATMDHODH | |
| SCHEMBL17307062 | 0.88 | KDM4E (0.45) | KMT2AMEN1METAP1ATMDHODH | |
| SCHEMBL17307083 | 0.88 | DHODH (0.42) | KMT2AMEN1METAP1ATMDHODH | |
| SCHEMBL17306713 | 0.88 | WHR1 (0.42) | KMT2AMEN1METAP1ATMDHODH | |
| SCHEMBL17306469 | 0.86 | LMNA (0.38) | KMT2AMEN1METAP1ATMDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |