Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | WHR1 | P49842 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306446 | 1.00 | HPGD (0.53) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL17306587 | 1.00 | HPGD (0.53) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL17306599 | 0.93 | MEN1 (0.55) | HPGDMEN1KMT2AATMWHR1 | |
| SCHEMBL17306569 | 0.92 | HPGD (0.48) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL17306439 | 0.92 | HPGD (0.47) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL17306589 | 0.91 | HPGD (0.47) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL17307089 | 0.90 | MKNK1 (0.52) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL17306700 | 0.90 | MKNK1 (0.52) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL17306453 | 0.89 | HPGD (0.45) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL18504039 | 0.89 | MEN1 (0.56) | HPGDMEN1KMT2AATMMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |