Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.37 |
| ▸ | WHR1 | P49842 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307085 | 0.90 | PIK3CA (0.42) | HIF1AWHR1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17306447 | 0.87 | MTOR (0.41) | HIF1AWHR1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17307087 | 0.85 | CYP2A6 (0.43) | HIF1APIK3CDPIK3CAPIK3CBMTOR | |
| SCHEMBL17307097 | 0.85 | CYP2A6 (0.43) | HIF1APIK3CDPIK3CAPIK3CBMTOR | |
| SCHEMBL17307086 | 0.81 | WHR1 (0.42) | HIF1AWHR1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17307080 | 0.81 | DHODH (0.43) | HIF1AWHR1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17306699 | 0.81 | DHODH (0.43) | HIF1AWHR1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17306430 | 0.81 | MTOR (0.45) | WHR1PIK3CDPIK3CAPIK3CBMTOR | |
| SCHEMBL17306754 | 0.81 | DHODH (0.43) | HIF1AWHR1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17306478 | 0.81 | WHR1 (0.45) | HIF1AWHR1PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |