Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307308 | 0.80 | TYR (0.40) | KDM4EHSD17B10TYRMEN1MMP2 | |
| SCHEMBL7916946 | 0.75 | TDP1 (0.43) | KDM4EALDH1A1ESR1ESR2GAA | |
| SCHEMBL6250707 | 0.75 | TDP1 (0.43) | KDM4EALDH1A1ESR1ESR2GAA | |
| SCHEMBL7164452 | 0.75 | TDP1 (0.43) | KDM4EALDH1A1ESR1ESR2GAA | |
| SCHEMBL5838521 | 0.75 | TDP1 (0.43) | KDM4EALDH1A1ESR1ESR2GAA | |
| SCHEMBL689027 | 0.75 | TDP1 (0.43) | KDM4EALDH1A1ESR1ESR2GAA | |
| SCHEMBL240779 | 0.75 | TDP1 (0.43) | KDM4EALDH1A1ESR1ESR2GAA | |
| SCHEMBL2919943 | 0.73 | TDP1 (0.41) | ALDH1A1ESR1ESR2GAAMAPT | |
| SCHEMBL28293995 | 0.73 | TDP1 (0.41) | ALDH1A1ESR1ESR2GAAMAPT | |
| Phosphine SCHEMBL10831576 | 0.73 | TDP1 (0.41) | ALDH1A1ESR1ESR2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184296-A1 | ANTIMICROBIAL PHARMACEUTICAL COMPOSITIONS WITH MULTIPLE DRUG RESISTANCE INHIBITING PROPERTIES | FRIEDHOFF LAWRENCE T (US) | 2015-12-03 | — | — | WO | disclosed |