Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | BID | P55957 | 7/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 6/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.33 |
| ▸ | F3 | P13726 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307113 | 0.80 | KDM4E (0.31) | TYRMMP2MAPTKDM4EHSD17B10 | |
| SCHEMBL12195876 | 0.75 | TYR (0.40) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL25608103 | 0.75 | TYR (0.40) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL15214282 | 0.74 | TYR (0.64) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL17988280 | 0.74 | TYR (0.46) | TYRMAPTALOX15MEN1TP53 | |
| SCHEMBL12733119 | 0.74 | TYR (0.64) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL240779 | 0.71 | TDP1 (0.43) | MAPTKDM4ECYP3A4HTTTDP1 | |
| SCHEMBL689027 | 0.71 | TDP1 (0.43) | MAPTKDM4ECYP3A4HTTTDP1 | |
| SCHEMBL7164452 | 0.71 | TDP1 (0.43) | MAPTKDM4ECYP3A4HTTTDP1 | |
| SCHEMBL5838521 | 0.71 | TDP1 (0.43) | MAPTKDM4ECYP3A4HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184296-A1 | ANTIMICROBIAL PHARMACEUTICAL COMPOSITIONS WITH MULTIPLE DRUG RESISTANCE INHIBITING PROPERTIES | FRIEDHOFF LAWRENCE T (US) | 2015-12-03 | — | — | WO | disclosed |