SCHEMBL17307447

SCHEMBL17307447

CC1(C)c2ccc(-c3ccc4ccccc4c3)cc2-c2c1ccc1c2sc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.37
MAPT P10636 1/20 0.34
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
PTGER3 P43115 2/20 0.33
S1PR5 Q9H228 5/20 0.32
S1PR4 O95977 4/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GSTP1 P09211 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
ALK Q9UM73 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
PARP14 Q460N5 1/20 0.30
GPR3 P46089 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17945367 0.94 ALOX5 (0.34) ALOX5MAPTLPLLIPGPTGER3
SCHEMBL17945139 0.94 ALOX5 (0.36) ALOX5MAPTLPLLIPGS1PR5
SCHEMBL17307469 0.88 ALOX5 (0.39) ALOX5MAPTATML3MBTL1PARP14
SCHEMBL21791190 0.88 ALOX5 (0.31) ALOX5LPLLIPG
SCHEMBL16170187 0.87 ALOX5 (0.35) ALOX5MAPTS1PR5S1PR4ATM
SCHEMBL17944357 0.87 ALOX5 (0.33) ALOX5MAPTLPLLIPGESR1
SCHEMBL17307454 0.87 ALOX5 (0.38) ALOX5MAPTPARP14GPR3
SCHEMBL17307463 0.86 ALOX5 (0.40) ALOX5MAPTALKPARP14GPR3
SCHEMBL17932230 0.86 ALOX5 (0.37) ALOX5MAPTL3MBTL1PARP14GPR3
SCHEMBL16170203 0.85 ALOX5 (0.36) ALOX5MAPTS1PR5S1PR4GSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9653690-B2 Organic compound, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2017-05-16 US disclosed
US-9653690-B2 Organic compound, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2017-05-16 US disclosed
US-20150349270-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2015-12-03 US disclosed
US-20150349270-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150349270-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OXER1, OR10J3 ALOX5 798/4885MAPT 2444/4885LPL 3457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.