SCHEMBL17307459

SCHEMBL17307459

CC1(C)c2ccc(-c3ccc(-c4cc(-c5ccccc5)nc(-c5ccccc5)c4)cc3)cc2-c2c1ccc1c2sc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
LIMK1 P53667 2/20 0.32
PIM3 Q86V86 2/20 0.32
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
ACACA Q13085 1/20 0.32
PIM1 P11309 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
ROCK1 Q13464 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP19A1 P11511 1/20 0.31
DHODH Q02127 1/20 0.30
F9 P00740 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17307420 1.00 ALOX5 (0.34) ALOX5MEN1KMT2AMAPTLIMK1
SCHEMBL17307402 0.99 ALOX5 (0.34) ALOX5MEN1KMT2AMAPTLIMK1
SCHEMBL17307425 0.97 ALOX5 (0.36) ALOX5MEN1KMT2AMAPTTNKS
SCHEMBL17307438 0.94 ALOX5 (0.38) ALOX5MAPTF9
SCHEMBL17307457 0.93 MEN1 (0.36) ALOX5MEN1KMT2AMAPTLIMK1
SCHEMBL17307436 0.93 ALOX5 (0.38) ALOX5MAPTLIMK1TNKSTNKS2
SCHEMBL17307444 0.92 ALOX5 (0.37) ALOX5MAPTTNKSTNKS2ACACA
SCHEMBL17307421 0.92 MEN1 (0.34) ALOX5MEN1KMT2AMAPTTNKS
SCHEMBL17307454 0.91 ALOX5 (0.38) ALOX5MAPTLIMK1PIM3TNKS
SCHEMBL17307409 0.90 MEN1 (0.35) ALOX5MEN1KMT2AMAPTTNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9653690-B2 Organic compound, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2017-05-16 US disclosed
US-9653690-B2 Organic compound, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2017-05-16 US disclosed
US-20150349270-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2015-12-03 US disclosed
US-20150349270-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150349270-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OXER1, OR10J3 ALOX5 798/4885MEN1 2365/4885KMT2A 4093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.