Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 4/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.58 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 4/20 | 0.58 |
| ▸ | GSK3B | P49841 | 4/20 | 0.58 |
| ▸ | CSNK1G2 | P78368 | 4/20 | 0.58 |
| ▸ | PRKD2 | Q9BZL6 | 4/20 | 0.58 |
| ▸ | CSNK1G1 | Q9HCP0 | 4/20 | 0.58 |
| ▸ | CSNK1G3 | Q9Y6M4 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | GSK3A | P49840 | 3/20 | 0.58 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.58 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.58 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | LYN | P07948 | 1/20 | 0.58 |
| ▸ | AKT2 | P31751 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20969778 | 0.89 | PRKD3 (0.52) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 | |
| SCHEMBL12023544 | 0.81 | CSNK1E (0.64) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 | |
| SCHEMBL3519701 | 0.81 | MAPK9 (0.58) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 | |
| SCHEMBL12023386 | 0.81 | PRKD3 (0.61) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 | |
| SCHEMBL1728799 | 0.81 | CSNK1E (0.65) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 | |
| SCHEMBL12154383 | 0.81 | MAPK9 (0.70) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 | |
| SCHEMBL3524010 | 0.81 | PRKD3 (0.59) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 | |
| SCHEMBL3522612 | 0.81 | MAPK9 (0.58) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 | |
| SCHEMBL1730222 | 0.81 | PTGS2 (0.66) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 | |
| SCHEMBL3524969 | 0.80 | CSNK1E (0.71) | PRKD3MAP4K4MAPK8MAPK9CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483166-B1 | IMIDAZOOXAZOLE DERIVATIVE HAVING ANTITUMOR EFFECT, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | KOREA INST SCI & TECH (KR) | 2023-11-01 | — | — | EP | disclosed |
| US-11332479-B2 | Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-05-17 | — | — | US | disclosed |
| EP-3845539-A1 | IMIDAZOOXAZOLE DERIVATIVE HAVING ANTITUMOR EFFECT, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Korea Institute of Science and Technology (KR) | 2021-07-07 | — | — | EP | disclosed |
| US-20200131199-A1 | IMIDAZOOXAZOLE DERIVATIVE HAVING ANTITUMOR EFFECT, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-04-30 | — | — | US | disclosed |
| US-10570155-B2 | Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-02-25 | — | — | US | disclosed |
| US-20190211032-A1 | IMIDAZOOXAZOLE DERIVATIVE HAVING ANTITUMOR EFFECT, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-07-11 | — | — | US | disclosed |
| EP-3483166-A1 | IMIDAZOOXAZOLE DERIVATIVE HAVING ANTITUMOR EFFECT, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Korea Institute of Science and Technology (KR) | 2019-05-15 | — | — | EP | disclosed |
| US-20110301160-A1 | Inhibitors of P38 and Methods of Using the Same | ARQULE, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301160-A1 | Inhibitors of P38 and Methods of Using the Same | ARQULE, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301160-A1 | Inhibitors of P38 and Methods of Using the Same | ARQULE, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| EP-1633758-B1 | IMIDAZOTHIAZOLES AND IMIDAZOXAZOLE DERIVATIVES AS INHIBITORS OF P38 | ARQULE INC (US) | 2011-11-23 | — | — | EP | disclosed |
| EP-1633758-B1 | IMIDAZOTHIAZOLES AND IMIDAZOXAZOLE DERIVATIVES AS INHIBITORS OF P38 | ARQULE INC (US) | 2011-11-23 | — | — | EP | disclosed |
| US-7902192-B2 | Inhibitors of P38 and methods of using the same | ARQULE, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| US-7902192-B2 | Inhibitors of P38 and methods of using the same | ARQULE, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| US-7902192-B2 | Inhibitors of P38 and methods of using the same | ARQULE, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-2251343-A1 | IMIDAZOTHIAZOLES AS P38-KINASE-INHIBITORS | ARQULE, INC. (US) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251343-A1 | IMIDAZOTHIAZOLES AS P38-KINASE-INHIBITORS | ARQULE, INC. (US) | 2010-11-17 | — | — | EP | disclosed |
| US-20070270418-A1 | Inhibitors of P38 and Methods of Using the Same | ARQULE, INC. | 2007-11-22 | — | — | US | disclosed |
| US-20070270418-A1 | Inhibitors of P38 and Methods of Using the Same | ARQULE, INC. | 2007-11-22 | — | — | US | disclosed |
| US-20070270418-A1 | Inhibitors of P38 and Methods of Using the Same | ARQULE, INC. | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131199-A1 | IMIDAZOOXAZOLE DERIVATIVE HAVING ANTITUMOR EFFECT, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | TPMT, MYD88, IDO1 | PRKD3 1507/4885MAP4K4 2650/4885MAPK8 3370/4885 |
| US-10570155-B2 | Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same | TPMT, MYD88, IDO1 | PRKD3 1507/4885MAP4K4 2650/4885MAPK8 3370/4885 |
| US-11332479-B2 | Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same | TPMT, MYD88, IDO1 | PRKD3 1507/4885MAP4K4 2650/4885MAPK8 3370/4885 |
| US-20190211032-A1 | IMIDAZOOXAZOLE DERIVATIVE HAVING ANTITUMOR EFFECT, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | TPMT, MYD88, IDO1 | PRKD3 1507/4885MAP4K4 2650/4885MAPK8 3370/4885 |
| US-20070270418-A1 | Inhibitors of P38 and Methods of Using the Same | MAPK1, MAPK8, MAPK7 | PRKD3 541/4885MAP4K4 44/4885MAPK8 2/4885 |
| US-20110301160-A1 | Inhibitors of P38 and Methods of Using the Same | MAPK1, MAPK7, MAPK8 | PRKD3 507/4885MAP4K4 43/4885MAPK8 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.