Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 4/20 | 0.43 |
| ▸ | AKT2 | P31751 | 4/20 | 0.43 |
| ▸ | AKT3 | Q9Y243 | 4/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | GJB2 | P29033 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17309400 | 1.00 | CETP (0.45) | CETPMAPK1AKT1AKT2AKT3 | |
| SCHEMBL17309226 | 1.00 | CETP (0.45) | CETPMAPK1AKT1AKT2AKT3 | |
| SCHEMBL17309229 | 1.00 | CETP (0.45) | CETPMAPK1AKT1AKT2AKT3 | |
| SCHEMBL7167831 | 1.00 | CETP (0.45) | CETPMAPK1AKT1AKT2AKT3 | |
| SCHEMBL19079080 | 1.00 | CETP (0.45) | CETPMAPK1AKT1AKT2AKT3 | |
| SCHEMBL19079073 | 1.00 | CETP (0.45) | CETPMAPK1AKT1AKT2AKT3 | |
| SCHEMBL19079084 | 1.00 | CETP (0.45) | CETPMAPK1AKT1AKT2AKT3 | |
| SCHEMBL17817172 | 1.00 | CETP (0.45) | CETPMAPK1AKT1AKT2AKT3 | |
| SCHEMBL19079083 | 1.00 | CETP (0.45) | CETPMAPK1AKT1AKT2AKT3 | |
| SCHEMBL22543399 | 0.91 | GJB2 (0.47) | AKT1AKT2AKT3PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179983-A1 | DI- AND TRI-CATIONIC GLYCOSYLATED ANTITUMOR ETHER LIPIDS, L-GUCOSYLATED GAELS AND RHAMNOSE-LINKED GAELS AS CYTOTOXIC AGENTS AGAINST EPITHELIAL CANCER CELLS AND CANCER STEM CELLS | THE UNIVERSITY OF MANITOBA (CA) | 2015-12-03 | — | — | WO | disclosed |