Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485748 | 0.84 | MEN1 (0.56) | MAPTNPSR1MEN1KMT2ACASP1 | |
| SCHEMBL28302465 | 0.79 | NOS3 (0.47) | MAPTNOS3NOS1NOS2RAB9A | |
| SCHEMBL29746229 | 0.73 | NOS3 (0.53) | MAPTMEN1KMT2AL3MBTL1NOS3 | |
| SCHEMBL2127063 | 0.72 | NOS3 (0.57) | MAPTMEN1KMT2ANOS3NOS1 | |
| SCHEMBL13961627 | 0.69 | HRH4 (0.46) | MAPTNPSR1MEN1KMT2ACASP1 | |
| SCHEMBL16372983 | 0.68 | NOS3 (0.52) | MAPTNOS3NOS1NOS2BCHE | |
| SCHEMBL15066599 | 0.68 | BCHE (0.42) | MAPTNPSR1MEN1KMT2ACASP1 | |
| SCHEMBL11887426 | 0.67 | NPSR1 (0.54) | MAPTNPSR1MEN1KMT2ACASP1 | |
| SCHEMBL20675773 | 0.67 | NPSR1 (0.44) | MAPTNPSR1MEN1KMT2ACASP1 | |
| SCHEMBL5958858 | 0.66 | NOS3 (0.59) | MAPTMEN1KMT2ANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761614-B1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |