Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17309671 | 0.93 | GAA (0.73) | GAALMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL17309683 | 0.85 | LMNA (0.57) | GAALMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL17481131 | 0.84 | GAA (0.81) | GAALMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL18381278 | 0.82 | GAA (0.77) | GAALMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL10045076 | 0.82 | GAA (0.70) | GAALMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL12472614 | 0.82 | HTT (0.67) | GAALMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL1231977 | 0.81 | GAA (0.76) | GAALMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL12999426 | 0.81 | GAA (0.75) | GAALMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL17309691 | 0.81 | SMN1; SMN2 (0.57) | GAALMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL13405878 | 0.81 | HTT (0.84) | GAALMNASMN1; SMN2HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9546232-B2 | Rubber composition, and pneumatic tire using same | BRIDGESTONE CORPORATION (JP) | 2017-01-17 | — | — | US | disclosed |
| US-20150353657-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2952541-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2015-12-09 | — | — | EP | disclosed |