Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 15/20 | 0.77 |
| ▸ | JAK2 | O60674 | 4/20 | 0.50 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | TYK2 | P29597 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17310235 | 0.90 | ALK (0.72) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL20590754 | 0.89 | ALK (0.78) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL15932986 | 0.87 | ALK (1.00) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL17310117 | 0.81 | ALK (0.75) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL15933019 | 0.79 | ALK (0.64) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL15933001 | 0.76 | ALK (1.00) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL17404656 | 0.74 | ALK (0.76) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL15933012 | 0.74 | ALK (1.00) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL15933007 | 0.71 | ALK (0.56) | ALKJAK2JAK1TYK2JAK3 | |
| SCHEMBL15147544 | 0.69 | ALK (0.67) | ALKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2952510-A1 | SUBSTITUTED 2-AMINOPYRIDINE PROTEIN KINASE INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co.,Ltd (CN) | 2015-12-09 | — | — | EP | disclosed |