Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | GPX4 | P36969 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17310341 | 0.93 | TRPV1 (0.49) | TRPV1FAAHMEN1KMT2ACYP1A2 | |
| SCHEMBL17310327 | 0.91 | TRPV1 (0.49) | TRPV1FAAHGPX4 | |
| SCHEMBL17310343 | 0.89 | TRPV1 (0.47) | TRPV1FAAHMAPK10MAPK8 | |
| SCHEMBL17310353 | 0.87 | TRPV1 (0.42) | TRPV1FAAHGPX4MAPK10MAPK8 | |
| SCHEMBL17310289 | 0.87 | TRPV1 (0.49) | TRPV1GSK3BMAPK10MAPK8 | |
| SCHEMBL17310270 | 0.85 | TRPV1 (0.43) | TRPV1FAAHMAPK10MAPK8 | |
| SCHEMBL17310344 | 0.85 | TRPV1 (0.40) | TRPV1FAAHMEN1KMT2AGPX4 | |
| SCHEMBL17310310 | 0.85 | TRPV1 (0.49) | TRPV1FAAH | |
| SCHEMBL2273052 | 0.84 | TRPV1 (0.66) | TRPV1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL17310340 | 0.84 | PARP1 (0.42) | TRPV1FAAHMAPK10MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1714961-B1 | INDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2015-12-09 | — | — | EP | claimed |