Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17310327 | 0.91 | TRPV1 (0.49) | TRPV1FAAH | |
| SCHEMBL17310355 | 0.85 | MTHFD2 (0.46) | TRPV1FAAHMAPK10MAPK8 | |
| SCHEMBL17310302 | 0.85 | CFTR (0.40) | TRPV1FAAHMAPK10 | |
| SCHEMBL17310310 | 0.85 | TRPV1 (0.49) | TRPV1FAAH | |
| SCHEMBL17310312 | 0.84 | TRPV1 (0.49) | TRPV1FAAHMAPK10MAPK8 | |
| SCHEMBL17310272 | 0.84 | TRPV1 (0.47) | TRPV1FAAHMAPK10 | |
| SCHEMBL17310341 | 0.84 | TRPV1 (0.49) | TRPV1FAAHMAPK10MAPK8 | |
| SCHEMBL17310343 | 0.84 | TRPV1 (0.47) | TRPV1FAAHMAPK10MAPK8 | |
| SCHEMBL17310277 | 0.84 | TRPV1 (0.49) | TRPV1FAAH | |
| SCHEMBL17310344 | 0.83 | TRPV1 (0.40) | TRPV1FAAHMAPK10MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1714961-B1 | INDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2015-12-09 | — | — | EP | claimed |