Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723775 | 0.91 | TRPV1 (0.55) | TRPV1NPY5RMEN1KMT2AKDM4E | |
| SCHEMBL2724809 | 0.91 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL2726587 | 0.90 | TRPV1 (0.56) | TRPV1KDM4EMAPTFAAHPDGFRB | |
| SCHEMBL31679062 | 0.90 | TRPV1 (0.56) | TRPV1KDM4EMAPTFAAHPDGFRB | |
| SCHEMBL17310441 | 0.89 | TRPV1 (0.40) | TRPV1NPY5RMEN1KMT2AKDM4E | |
| SCHEMBL2725244 | 0.87 | TRPV1 (0.59) | TRPV1NPY5RKDM4EMAPT | |
| SCHEMBL31679069 | 0.87 | TRPV1 (0.59) | TRPV1NPY5RKDM4EMAPT | |
| SCHEMBL2724882 | 0.82 | TRPV1 (0.58) | TRPV1KMT2AMAPTFAAH | |
| SCHEMBL31679064 | 0.82 | TRPV1 (0.58) | TRPV1KMT2AMAPTFAAH | |
| SCHEMBL19946397 | 0.80 | TRPV1 (0.56) | TRPV1KMT2AKDM4EMAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150352105-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-12-10 | — | — | US | disclosed |