Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244557 | 1.00 | ALDH1A1 (0.35) | ALDH1A1CYP2C19TP53TSHRSLC7A5 | |
| SCHEMBL7650264 | 0.82 | CPT2 (0.38) | ALDH1A1TP53TSHRSLC7A5 | |
| SCHEMBL5711892 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP2C19TP53TSHRGAA | |
| SCHEMBL31296595 | 0.75 | ALDH1A1 (0.36) | ALDH1A1CYP2C19TP53TSHRSLC7A5 | |
| SCHEMBL303935 | 0.75 | ALDH1A1 (0.36) | ALDH1A1CYP2C19TP53TSHRSLC7A5 | |
| SCHEMBL2815553 | 0.73 | CPT2 (0.41) | ALDH1A1CYP2C19TP53TSHRGAA | |
| SCHEMBL20262331 | 0.73 | TP53 (0.35) | ALDH1A1CYP2C19TP53SLC7A5 | |
| SCHEMBL14261024 | 0.72 | ALDH1A1 (0.38) | ALDH1A1CYP2C19TP53TSHRSLC7A5 | |
| SCHEMBL9143730 | 0.72 | ALDH1A1 (0.38) | ALDH1A1CYP2C19TP53TSHRSLC7A5 | |
| SCHEMBL6057041 | 0.72 | ALDH1A1 (0.38) | ALDH1A1CYP2C19TP53TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150353941-A1 | Genetically Modified Biological Cells | O'KEEFE THERESA (US) | 2015-12-10 | — | — | US | disclosed |