Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1731876 | 0.91 | F2R (0.39) | F2R | |
| Trifluoroacetic Acid SCHEMBL1728671 | 0.90 | F2R (0.37) | F2R | |
| Bromide SCHEMBL1732250 | 0.84 | F2R (0.36) | F2R | |
| Bromide SCHEMBL1729257 | 0.81 | F2R (0.37) | F2RKDM4EMAPTRAB9A | |
| Bromide SCHEMBL1732473 | 0.81 | F2R (0.35) | F2R | |
| Bromide SCHEMBL1729969 | 0.81 | F2R (0.36) | F2RKDM4EMAPTRAB9ASMN1; SMN2 | |
| Bromide SCHEMBL5483964 | 0.80 | F2R (0.34) | F2R | |
| SCHEMBL14449138 | 0.79 | F2R (0.32) | F2R | |
| SCHEMBL14468883 | 0.79 | F2R (0.32) | F2R | |
| Trifluoroacetic Acid SCHEMBL1730316 | 0.79 | F2R (0.47) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |