Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13561242 | 0.98 | SLC2A1 (0.51) | SLC2A1TLR4DGKAPTGS1PTGS2 | |
| SCHEMBL10325673 | 0.98 | SLC2A1 (0.51) | SLC2A1TLR4DGKAPTGS1PTGS2 | |
| SCHEMBL10325671 | 0.98 | SLC2A1 (0.51) | SLC2A1TLR4DGKAPTGS1PTGS2 | |
| SCHEMBL17318244 | 0.95 | TLR4 (0.49) | SLC2A1TLR4DGKALPAR1LPAR3 | |
| SCHEMBL17318241 | 0.94 | TLR4 (0.51) | SLC2A1TLR4DGKAMAPTLPAR1 | |
| SCHEMBL17866084 | 0.94 | TLR4 (0.51) | SLC2A1TLR4DGKAPTGS1PTGS2 | |
| SCHEMBL9228629 | 0.94 | TLR4 (0.51) | SLC2A1TLR4DGKAPTGS1PTGS2 | |
| SCHEMBL9231092 | 0.92 | TLR4 (0.53) | SLC2A1TLR4DGKAPTGS1PTGS2 | |
| SCHEMBL8506716 | 0.92 | TLR4 (0.53) | SLC2A1TLR4DGKAPTGS1PTGS2 | |
| SCHEMBL12427213 | 0.92 | TLR4 (0.53) | SLC2A1TLR4DGKAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152220-A1 | NICOTINAMIDE RIBOSIDE ANALOGS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2017-04-12 | — | — | EP | claimed |
| WO-2015186114-A1 | NICOTINAMIDE RIBOSIDE ANALOGS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2015-12-10 | — | — | WO | claimed |