Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN12 | Q05209 | 1/20 | 0.72 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.66 |
| ▸ | MMP3 | P08254 | 2/20 | 0.66 |
| ▸ | MMP13 | P45452 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15400060 | 0.88 | CISD1 (0.74) | AKR1B1PTPN1KMT2AMEN1 | |
| SCHEMBL15400058 | 0.88 | CISD1 (0.74) | AKR1B1PTPN1KMT2AMEN1 | |
| SCHEMBL12008437 | 0.88 | CISD1 (0.74) | AKR1B1PTPN1KMT2AMEN1 | |
| SCHEMBL8181294 | 0.88 | AKR1B1 (0.72) | AKR1B1 | |
| SCHEMBL8181292 | 0.88 | AKR1B1 (0.72) | AKR1B1 | |
| SCHEMBL12008457 | 0.86 | FFAR1 (0.74) | AKR1B1KMT2AMEN1L3MBTL1 | |
| SCHEMBL6886567 | 0.86 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1PTPN1MMP3 | |
| SCHEMBL10491513 | 0.86 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1PTPN1MMP3 | |
| SCHEMBL6886565 | 0.86 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1PTPN1MMP3 | |
| SCHEMBL10492188 | 0.85 | PTPN12 (0.79) | PTPN12PTPN22AKR1B1PTPN1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206412-B2 | Thioxothiazolidine inhibitors | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |