Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.71 |
| ▸ | MEN1 | O00255 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.64 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALPL | P05186 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008752 | 0.92 | KMT2A (0.82) | DDX3XKMT2AMEN1MAPTPOLB | |
| SCHEMBL11913684 | 0.90 | DDX3X (0.84) | DDX3XKMT2AMEN1MAPTPOLB | |
| SCHEMBL12008751 | 0.85 | DDX3X (0.80) | DDX3XKMT2AMEN1MAPTPOLB | |
| SCHEMBL11913683 | 0.85 | DDX3X (1.00) | DDX3XKMT2AMEN1MAPTPOLB | |
| SCHEMBL17319559 | 0.82 | KMT2A (0.72) | DDX3XKMT2AMEN1MAPTPOLB | |
| SCHEMBL12008967 | 0.82 | KMT2A (0.84) | KMT2AMEN1MAPTPOLBTDP1 | |
| SCHEMBL12008423 | 0.82 | KMT2A (1.00) | KMT2AMEN1MAPTPOLBTDP1 | |
| SCHEMBL11899368 | 0.81 | DDX3X (1.00) | DDX3XKMT2AMEN1MAPTPOLB | |
| SCHEMBL11899367 | 0.81 | DDX3X (1.00) | DDX3XKMT2AMEN1MAPTPOLB | |
| SCHEMBL11899366 | 0.81 | DDX3X (1.00) | DDX3XKMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206412-B2 | Thioxothiazolidine inhibitors | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |