Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 15/20 | 0.83 |
| ▸ | MEN1 | O00255 | 13/20 | 0.83 |
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.83 |
| ▸ | BLM | P54132 | 3/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.74 |
| ▸ | POLB | P06746 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.66 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17319553 | 0.91 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMTDP1 | |
| SCHEMBL12008605 | 0.91 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMTDP1 | |
| SCHEMBL12008604 | 0.90 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMTDP1 | |
| SCHEMBL17319549 | 0.90 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMTDP1 | |
| SCHEMBL18545509 | 0.88 | KMT2A (0.78) | KMT2AMEN1CTDSP1BLMTDP1 | |
| SCHEMBL12008603 | 0.87 | KMT2A (0.79) | KMT2AMEN1CTDSP1BLMTDP1 | |
| SCHEMBL12008423 | 0.85 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMTDP1 | |
| SCHEMBL12008606 | 0.85 | PTPN12 (0.76) | KMT2AMEN1CTDSP1BLMTDP1 | |
| SCHEMBL12008607 | 0.85 | KMT2A (0.75) | KMT2AMEN1CTDSP1BLMTDP1 | |
| SCHEMBL12008768 | 0.84 | CISD1 (0.79) | KMT2AMEN1CTDSP1BLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206412-B2 | Thioxothiazolidine inhibitors | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |