Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 17/20 | 1.00 |
| ▸ | MEN1 | O00255 | 15/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 7/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 8/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.81 |
| ▸ | NPC1 | O15118 | 3/20 | 0.81 |
| ▸ | PTPN12 | Q05209 | 4/20 | 0.77 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.77 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.77 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.77 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.77 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.68 |
| ▸ | MMP2 | P08253 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008604 | 1.00 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMPOLB | |
| SCHEMBL12008572 | 0.93 | KMT2A (0.89) | KMT2AMEN1CTDSP1BLMPOLB | |
| SCHEMBL12008778 | 0.91 | KMT2A (0.90) | KMT2AMEN1CTDSP1BLMPOLB | |
| SCHEMBL13446873 | 0.91 | KMT2A (0.83) | KMT2AMEN1CTDSP1BLMPOLB | |
| SCHEMBL17319563 | 0.90 | KMT2A (0.83) | KMT2AMEN1CTDSP1BLMPOLB | |
| SCHEMBL12008592 | 0.89 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMPOLB | |
| SCHEMBL17319553 | 0.89 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMPOLB | |
| SCHEMBL12008605 | 0.89 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMPOLB | |
| SCHEMBL12008570 | 0.89 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMPOLB | |
| SCHEMBL12008751 | 0.87 | DDX3X (0.80) | KMT2AMEN1CTDSP1BLMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206412-B2 | Thioxothiazolidine inhibitors | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |